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The idea that any extract from cannabis can be a stimulant is a novel one and one that we are doing our best to understand here at PureKana.

It has been a solid three years since the farm bill of 2018 opened up the legalized hemp and cannabis market for Americans all over the country.

Since then, the amount of knowledge consumers have accrued about CBD and THC has been hard to quantify.

However, we look back at the days of the 1980s, with Nancy Reagan preaching complete abstinence from drugs, and we can see that the cornerstone of the messaging had to do with cannabis as a gateway drug. 

The repercussions of this political decision still reverberate today.

Armed with a lot more knowledge about cannabis, we can see the many health benefits that the plant can provide without even mentioning THC or marijuana.

THC, or tetrahydrocannabinol, is not alone cannabinoid existing all on its own. It is a descendant of other, lesser-known cannabinoids, and it has an array of “cousin” cannabinoids, one of which is THCV.

The uniqueness of THCV, combined with its relative rarity in cannabis crops grown domestically, makes it an incredibly fascinating cannabinoid to study and try out.

Today’s blog will be a synopsis of THCV’s scientific origins and its purpose as a cannabinoid that can provide you with a burst of energy, assisting with your metabolic rate and suppressing your appetite. 

What Is THCV?

THCV, mysterious as it is, is present in small amounts in most cannabis plants, whether hemp or marijuana. THCV is shorthand for tetrahydrocannabivarin, a close relative of THC.

This strain is considered a homologue, which means it is a repeating molecule that distinguishes it from its “parent” strain.

THCV boasts a three-carbon molecule (propyl molecule), while old THC has a five-carbon pentyl molecule. 

In addition, THCV interacts with the body in quite a different way than other cannabinoids do, especially further from THC and CBD. We mean that it is an antagonist at the body’s cannabinoid receptors.

If that still confuses you, think of it this way: the body has an endocannabinoid system, a system vital to the everyday functions of the human body. It governs things like fertility, immunity, mood, sleep, circadian rhythms, and appetite.

This system has the molecules that it utilizes to keep all these functions in check, and these are called anandamide (AEA) and 2-arachidonoylglycerol (2-AG).

The body uses these molecules as it sees fit, in a somewhat opaque way that is still being studied.

When an individual inhales THC or CBD or ingests it, these receptors become overwhelmed by the individual cannabinoids that attach to the receptors.

In turn, changing the way they behave and temporarily suspending the natural order of the molecules above.

This results in some of the more well-known side effects of THC and CBD. Including the euphoria, sedative effects, increased appetite, and impaired motor skills. 

THC and CBD are considered “agonists,” meaning they enhance and change the behavior of cannabinoids at the site.

On the other hand, THCV is an antagonist, which brings the opposite effect, and we will describe the implication of this in the next section.

THCV Stimulant Facts

So we have established that THCV is an antagonist at the receptor sites, meaning that it has an entirely different and opposite effect than the effects induced by CBD and THC.

The word opposite is vital here. THCV’s antagonist activity at the body’s cannabinoid receptors means that it gives you opposite effects from THC.

For you, this means crushed appetite, a sense of clear-headedness, enhanced concentration and creativity, and above all, increased energy.

In addition, psychoactive effects are unlikely with THCV, as it is only known to induce a “high” in much higher doses than the ones you are currently likely to find on the market.

The THCV level needed for stimulant effects is not very high, at least nothing about 15-20 mg. 

The crushed appetite as a result of THCV’s antagonist activities in the body is currently being studied and showing very promising findings so far.

This has pretty exciting implications for the wellness industry if more studies bear out and THCV becomes part of the fight against America’s obesity epidemic. 

Additionally, the anti-inflammatory elements that have been uncovered in studies show promise, at least as much as the studies being employed as CBD has taken the wellness industry by storm.  

Comparison With Other Cannabinoids

So, what can you expect from THCV when you stack it up against other cannabinoids? We will go through some of the main ones here in this section.

THC, as you may already be aware, is a highly psychoactive compound, more or less primed for recreational use. It is far more sedating, hunger-inducing, and euphoric than THCV.

CBD, like THC, will not get you high. However, they both share anti-inflammatory properties and are ripe for stacking alongside each other.

In addition, CBD has more of a calming, decompressing effect, while THCV is more stimulating, so keep that in mind.

CBN and CBG are non-psychoactive cannabinoids, with CBN leaning more towards the sedative or sleep aid appeal and CBG showing signs of antibiotic and antibacterial elements in critical studies. 

THCV So Far: Where To Find It, And What Consumers Think 

THCV, as of this writing, is a bit of a complex cannabinoid to find, but not impossible at all. It comes in 10 mg drops and sprays and your classic tincture.

However, if you live in a state with completely legalized cannabis, it may be easier for you to try out THCV from certain recreational cannabis strains.

This could be in the form of Red Congolese, Doug’s Varin, Jack The Ripper, and Pineapple Purps. 

Consumers have reported (via Reddit) their love of the stimulant effect when using high-THCV strains and the enhanced creative product for artists.

In addition, they say mild psychoactivity when paired with recreational cannabis and an overall sense of well-being and enhanced mood.

Watch this space for more updates on the innovative new THCV cannabinoid! 


Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice.

The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice.

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